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La ligne 43 est exploitée avec un parc de 5 véhicules standards offrant les fréquences suivantes :
La ligne fonctionne du lundi au vendredi de 5h25 à 0h25, le samedi à partir de 5h35 et les dimanches et fêtes à partir de 6h05 environ. En soirée après 22h30, le tronçon entre Vallet et Loëx-Hôpital n'est pas desservi. (source Wikipédia)
